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Your design can be implemented to show public facing function of you plone site with a radically different look from the Plone default style. Editing/Management of the plone site can be done using a default Plone skin which allows you to leverage Plone's excellent user interface design where you need it most.

Plone skin tutorials + related links:

Putting a new look on Plone: a real-world example

DIYPloneStyle: Creating a Custom Style for Plone (2.1)